2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W779504
    b-Cortolone
    b-Cortolone is the metabolite of Cortisol (HY-N0583), that reveals relatively low biological activity.
    b-Cortolone
  • HY-137546
    Reduced Haloperidol
    Reduced Haloperidol (Haloperidol metabolite II) is an antipsychotic compound with neurotransmitter modulating activity. Reduced Haloperidol is commonly used to inhibit schizophrenia and other psychotic disorders. Reduced Haloperidol helps reduce the occurrence of hallucinations and delusions by inhibiting the activity of dopamine receptors.
    Reduced Haloperidol
  • HY-113864
    Diisobutyl carbinol
    Diisobutyl carbinol (DIBC) is an orally active organic solvent widely used as industrial intermediates and fragrance ingredient. Diisobutyl carbinol and Diisobutyl ketone are well interconverted metabolically in rats.
    Diisobutyl carbinol
  • HY-135389R
    Desmethyl Levofloxacin (Standard)
    Desmethyl Levofloxacin (Standard) is the analytical standard of Desmethyl Levofloxacin. This product is intended for research and analytical applications. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    Desmethyl Levofloxacin (Standard)
  • HY-169828
    Ketopynalin
    Ketopynalin (CGP-85903) is a metabolite of Vatalanib (HY-10203).
    Ketopynalin
  • HY-137522AS1
    Zidovudine Glucuronide-13C6
    Zidovudine Glucuronide-13C6 (3'-Azido-3'-deoxythymidine β-D-glucuronide-13C6) is 13C labeled Zidovudine O-β-D-glucuronide. Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine Glucuronide-<sup>13</sup>C<sub>6</sub>
  • HY-136457R
    2-NP-AHD (Standard)
    2-NP-AHD (Standard) is the analytical standard of 2-NP-AHD. This product is intended for research and analytical applications. 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents.
    2-NP-AHD (Standard)
  • HY-168799
    3-Methoxy prostaglandin F1α
    3-Methoxy prostaglandin F1α is an analog of PGF1α that can be metabolized by naturally occurring extracellular antibiotic resistance genes (eARGs) that enter the intestine via the food chain.
    3-Methoxy prostaglandin F1α
  • HY-103638R
    3-Methoxytyramine hydrochloride (Standard)
    3-Methoxytyramine (hydrochloride) (Standard) is the analytical standard of 3-Methoxytyramine (hydrochloride). This product is intended for research and analytical applications. 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1).
    3-Methoxytyramine hydrochloride (Standard)
  • HY-W707158
    Norfenfluramine hydrochloride
    Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, formed through N-dealkylation of Fenfluramine. Norfenfluramine hydrochloride is also a potent anorexiant. Norfenfluramine hydrochloride can regulate serotonergic neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects after acute administration.
    Norfenfluramine hydrochloride
  • HY-129708
    LU 2443
    LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h.
    LU 2443
  • HY-126833B
    Myristoyl coenzyme A triammonium
    Myristoyl coenzyme A triammonium (14:0 Coenzyme A) is a type of long-chain acyl-CoA, which is the activated form of long-chain fatty acids and serves as a crucial lipid metabolite.
    Myristoyl coenzyme A triammonium
  • HY-141410
    Fluticasone dimer impurity
    Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate. Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity.
    Fluticasone dimer impurity
  • HY-170629
    3,4-Dimethylmethcathinone metabolite hydrochloride
    3,4-Dimethylmethcathinone metabolite hydrochloride is a metabolite of 3,4-Dimethylmethcathinone. 3,4-Dimethylmethcathinone is a stimulant agent.
    3,4-Dimethylmethcathinone metabolite hydrochloride
  • HY-168367
    2-Hydroxyethylflurazepam
    2-Hydroxyethylflurazepam (compound II) is a metabolite of Flurazepam.
    2-Hydroxyethylflurazepam
  • HY-W012982R
    3-Amino-2-oxazolidinone (Standard)
    3-Amino-2-oxazolidinone (Standard) is the analytical standard of 3-Amino-2-oxazolidinone. This product is intended for research and analytical applications. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo.
    3-Amino-2-oxazolidinone (Standard)
  • HY-138176
    7-Hydroxyrisperidone
    7-Hydroxyrisperidone (7-RispOH) is a metabolite of Risperidone (HY-11018). Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist.
    7-Hydroxyrisperidone
  • HY-W653919
    SN-38 glucuronide-d3
    SN-38 glucuronide-d3 is deuterium labeled SN-38 glucuronide. SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer.
    SN-38 glucuronide-d<sub>3</sub>
  • HY-130318
    Quinidine N-oxide
    Quinidine N-oxide is a pharmacologically inactive metabolite of Quinidine (HY-B1751H). Quinidine is an active probe of CYP3A4.
    Quinidine N-oxide
  • HY-131422
    (Rac)-8-Hydroxy-efavirenz
    (Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz (HY-10572), a non-nucleoside HIV-1 reverse transcriptase inhibitor.
    (Rac)-8-Hydroxy-efavirenz
Cat. No. Product Name / Synonyms Application Reactivity